|
KMID : 0384320070280100762
|
|
Korean Journal of Family Medicine
2007 Volume.28 No. 10 p.762 ~ p.767
|
|
|
Leukocytosis Prevalence according to Smoking among Men
|
|
Kim Gwi-Sun
Park Il-Joong
Kong Mi-Hee
Lee Tae-Young
Joo Nam-Seok
Kim Kwang-Min
|
|
|
Abstract
|
|
|
Background: Cigarette smoke exposure accelerates the release of leukocytes from the bone marrow, which is postulated to be mediated by inflammatory cytokines and haematopoietic growth factors released from the lung.
Methods: The study population consisted of 2,270 healthy men above 20 years of age who had visited a health
promotion center in a university hospital from January 2005 to December 2005. Baseline health check, selfreported
cigarette smoking habit and blood sample were evaluated. The mean count of leukocytes and the leukocytosis prevalence according to smoking amounts were investigated.
Results: As the daily smoking amount was increased and as pack years smoked was increased, the mean total WBC count values and the prevalence of leukocytosis were higher (P=0.000). The odds ratio (OR) for leukocytosis
according to daily smoking amount compared to no smokers was 1.98 (95% confidence interval (CI) 1.01∼ 3.88) in those who smoked 1/2∼1 pack per day and 4.17 (95% CI 1.83∼9.48) in those who smoked more than 1 pack per day. The OR for leukocytosis according to smoking pack years compared to no smokers was 2.58 (95% CI 1.22∼5.42) in those who smoked 20∼30 pack years, 3.31 (95% CI 1.38∼7.93) in those who smoked 30∼ 40 pack years and 5.17 (95% CI 2.00∼13.32) in those who smoked more than 40 pack years.
Conclusion: The mean count of leukocytes and the prevalence of leukocytosis were higher in current smokers
than no smokers and ex-smokers
|
|
|
KEYWORD
|
|
|
smoking, leukocyte count, leukocytosis, men
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|